Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) comprise a strong class of instruments which might be redefining the boundaries of organic analysis. These chimeric nucleases are composed of programmable, sequence-specific DNA-binding modules linked to a nonspecific DNA cleavage area. ZFNs and TALENs allow a broad vary of genetic modifications by inducing DNA double-strand… Continue reading
